Defining Characteristics
Exercise intolerance w/ premature fatigue in anaerobic ex, stiffness/weakness in exercising muscles relieved by rest; rhabdomyolysis w/ intense ex, second wind phenomenon
Disease Development
Myophosphorylase deficiency, preventing the breakdown of glycogen to glucose (glycogen cannot be converted to G6P)
Potential Causes
Defect in glycogen breakdown
Lab/Imaging
Histology? Abnormal deposits of glycogen