Mucus membrane pemphigoid

defining characteristics

Red line along gingivial sulcus (white picket fence), no scarring.

disease development

Autoimmune blistering disorder where antibodies are directed at hemidesmosomes (sub-basal) so loss of epidermal attachment to basement membrane

potential causes

Autoantibodies against BPAG2, laminins, integrins

epidemiology

risk factors

labimaging

Histology? Subepidermal blister (white space btwn epidermis & dermis) (sub-basal split), healthy epidermis, +eosinophils (pink)
Dx confirmed w/ immunofluorescent Abs

conventional treatment

complications

prevention

Oral form of Mucus Membrane Pemphigoid has better prognosis (very little scarring)

protocols