Pemphigus foliaceus

defining characteristics

disease development

Autoimmune blistering disoder where antibodies (IgG) attack intra-epidermal (suprabasal) proteins of the desmosome, resulting in compromised cell-cell adhesion [basal layer splits from spinous layer]

potential causes

Autoantibodies against
desmoglein 1

epidemiology

risk factors

labimaging

conventional treatment

Immunosuppressants, corticosteroids

complications

Side effects of steroids

prevention

protocols