Home Pemphigus: Pemphigus foliaceus

Pemphigus: Pemphigus foliaceus

Types

Disease Development

Autoimmune blistering disoder where antibodies (IgG) attack intra-epidermal (suprabasal) proteins of the desmosome, resulting in compromised cell-cell adhesion [basal layer splits from spinous layer]

Potential Causes

Autoantibodies against
desmoglein 1

Conventional Treatment

Immunosuppressants, corticosteroids

Complications

Side effects of steroids