Varicella Zoster Virus (VZV) (Shingles)

defining characteristics

PAINFUL, DERMATOMAL vesicles, crusted papules,
erosions often in unilateral fashion

disease development

VZV goes latent after active infection/vaccination in the ganglia until risk factors cause reactivation of varicella zoster virus
NOT contagious (represents reactivation state) but patients with varicella zoster can transmit chicken pox to those who have never had it

potential causes

Varicella zoster virus

epidemiology

Lifetime risk of 10-20%

risk factors

Advancing age immunosuppression Stress!

labimaging

Clinical Tzanck prep
DFA (distinguish HSV from VZV) Viral Cx
Bx (rare)

conventional treatment

ORAL ANTI-VIRALS ASAP!! (w/I
first 48-72h)

complications

POST-HERPETIC NEURALGIA
dissemination
transmission of varicella (chicken pox)

prevention

Prevention with immunization w/ zoster in people > 50y.o.

protocols